Methods in molecular biology (Clifton, N.J.)HumansDNA Copy Number VariationsMultiplex Polymerase Chain ReactionInduced Pluripotent Stem CellsCells
Method for Validation Multiplexed Droplet Digital PCR for the Detection of Copy Number Variants in Cultured Human Pluripotent Stem Cells.
Said Assou, Reda Zenagui, Juline Vincent, Laurent Manchon, John De Vos
Published: 202610.1007/978-1-0716-4767-7_9
Abstract
Human-induced pluripotent stem cells (hiPSCs) have broad applications in basic research and cell-based regenerative medicine. Maintaining a stable genome in culture is crucial for the clinical use of hiPSCs. Indeed, their continuous propagation drive…
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