Methods in molecular biology (Clifton, N.J.)
High-Throughput Drug Testing and Synergy Evaluation in Patient-Derived Tumor Organoids: A Practical Guide.
Ayse Mine Yilmaz, Ali Sahin, Dila Sener-Akcora, Muharrem Okan Cakir, Taha Bahsi, Mustafa Ozdogan, Betul Karademir-Yilmaz
Published: 202510.1007/7651_2025_676
Abstract
High-throughput drug testing combined with synergy evaluation in patient-derived tumor organoids (PDOs) represents a robust methodological approach to identify effective therapeutic combinations. PDOs retain tumor heterogeneity and the three-dimensio…
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