Handbook of experimental pharmacologyHumansSignal TransductionReceptorsG-Protein-CoupledAnimals
Agonism and Biased Signaling.
Terry Kenakin
Published: 202610.1007/164_2025_770
Abstract
This chapter considers biased signaling as a natural function of G protein-coupled receptors (GPCRs) in the form of probe dependence. Thus, any ligand that changes the conformation of the receptor (agonist, antagonist, or allosteric modulator) has th…
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