Small (Weinheim an der Bergstrasse, Germany)ProdrugsNanoparticlesReactive Oxygen SpeciesAnimalsRNA
Prodrug-Doped ROS-Responsive Lipid Nanoparticle for Enhanced mRNA Delivery and Synergistic Anti-Tumor Therapy.
Zhuoying Liang, Kuikun Yang, Mao Li
Published: 202510.1002/smll.202510759
Abstract
Lipid nanoparticSle (LNP) represents the most advanced mRNA delivery platform for the development of effective cancer therapeutics. Nevertheless, conventional LNP-mRNA systems are hindered by inadequate endosomal release capability and a lack of syne…
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