Small (Weinheim an der Bergstrasse, Germany)
Reshape Intracellular/Extracellular pH for Enhanced Nanocatalytic Ferroptosis and cGAS-STING Activation Induced Immunotherapy.
Jinglang Gong, Hongxiang Huang, Maoyu Gao, Yiling Ruan, Ruifang Chen, Yaoting Li, Shouju Wang, Xiaolian Sun
Published: 202510.1002/smll.202510253
Abstract
Nanometal-based therapies face challenges arising from the overexpression of proton efflux transporters in cancer cells, which acidifies the extracellular tumor microenvironment (TME) while preserving a relatively neutral intracellular pH, thereby co…
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