Small (Weinheim an der Bergstrasse, Germany)MucusMucinsAnimalsHumansHydrophobic and Hydrophilic Interactions
Smart Supramolecular Core-Shell Aggregates with Mucin-Triggered Surface Switch for Effectively Overcoming Contradictory Mucus and Epithelium Barriers.
Xue Xu, Rui Zhang, Yangjia Liu, Jun Liu, Dan Li, Tiantian Ye, Shujun Wang
Published: 202610.1002/smll.202509532
Abstract
Rapid mucus permeation and fast epithelium uptake are essential yet paradoxical requirements for efficient oral nanocarriers. For example, hydrophilic and electroneutral surfaces favor fast muco-penetration, but hydrophobic and positively charged sur…
Preview only. Read the full abstract at the source