Statistics in medicineHumansAlgorithmsComputer SimulationNonlinear DynamicsModels
A Stability-Enhanced Lasso Approach for Covariate Selection in Non-Linear Mixed Effects Model.
Auriane Gabaut, Rodolphe Thiébaut, Cécile Proust-Lima, Mélanie Prague
Published: 202610.1002/sim.70407
Abstract
Non-linear mixed effects models (NLMEMs) defined by ordinary differential equations (ODEs) are central to modeling complex biological systems over time, particularly in pharmacometrics, viral dynamics, and immunology. However, selecting relevant cova…
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