Phytotherapy research : PTR
Cycloastragenol Alleviates Bone Cancer Pain by Targeting Sirt1 to Inhibit Neuronal Ferroptosis and Promote M2 Microglial Polarization in the Spinal Dorsal Horn of Rats.
Chengfei Xu, Kan Yue, Dongjie Wang, Fengwei Yin, Lei Wang, Bing Ma, Jiajun Xiao, Yuhua Li, Yinsheng Chen, Ziming Zhou, Xuewu Lin, Liang Cheng, Huadong Ni
Published: 202610.1002/ptr.70217
Abstract
Bone cancer pain (BCP) is a chronic and debilitating condition often accompanied by neuroinflammation, microglial activation, and neuronal damage, which are difficult to manage with current therapies. Cycloastragenol (CAG), a bioactive compound from…
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