Phytotherapy research : PTRJanus Kinase 1DermatitisAtopicAnimalsSTAT3 Transcription Factor
Sappanone A Exerted Strong Anti-Inflammatory Effects in the Treatment of Atopic Dermatitis Through IL-21R-Mediated JAK1/STAT3 Pathway.
Jiayi Li, Chenjie Liu, Jun Liu, Jinkang He, Cheng Wang, Pengcheng Ma, Lingjun Li, Hongyang Li
Published: 202610.1002/ptr.70123
Abstract
As a common dermatosis, atopic dermatitis (AD) is primarily driven by type 2 inflammation. Sappanone A (SA), derived from the traditional medicinal plant Caesalpinia sappan L., has demonstrated a broad range of anti-inflammatory activities in various…
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