Phytotherapy research : PTRAnimalsArachidonate 5-LipoxygenaseMiceMacrophagesMale
Isopimpinellin: A Promising Treatment for Colitis-Related Colorectal Cancer That Targets ALOX5-Mediated Macrophage Polarization.
Min Zhan, Qin Yi, Liang Yu, Qiankun Li, Murong Jiang, Dongsheng Wu, Mintao Jian, Hui Cao, Donghua Bin
Published: 202510.1002/ptr.70065
Abstract
Colitis-associated colon cancer (CAC) is a malignant tumor caused by long-term inflammation. Isopimpinellin, known for its anti-inflammatory and anti-tumor properties in areas beyond CAC, may target arachidonate 5-lipoxygenase (ALOX5). This study aim…
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