Pest management scienceHerbicidesMolecular Docking Simulation4-Hydroxyphenylpyruvate DioxygenasePyrazolesPlant Weeds
Design, synthesis, herbicidal activity evaluation, and molecular docking of novel cyclohexenone derivatives containing pyrazole group as potential HPPD inhibitors.
Yu Liu, Hao-Ran Hu, Juan Meng, Wen-Rui Li, Guang-Yu Dai, Shuai-Tao Hou, Min Chen, Ai-Min Lu, Chun-Long Yang, Wei-Hua Zhang
Published: 202610.1002/ps.70334
Abstract
BACKGROUND: 4-Hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27, HPPD), as a key enzyme for tyrosine decomposition, is a highly regarded herbicide target. In this work, a series of cyclohexenone derivatives containing a substituted pyrazole group were…
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