The Prostate
Comparative Digital Estrogen Receptor Alpha (ERα) Expression Analysis in Benign and Malignant Prostate Tissue of Men and Dogs.
Jennifer Lothion-Roy, Leonore Aeschlimann, Lea Anna Hiller, Sven Rottenberg, Nigel P Mongan, Catrin S Rutland, Emad Rakha, Alexander Dean, Mark A Rubin, Simone de Brot
Published: 202510.1002/pros.70111
Abstract
BACKGROUND: The dog is the only large mammal, other than humans, that commonly develops spontaneous prostate cancer (PCa) and is, therefore, considered a valuable model for comparative studies. Estrogens are critical for normal prostate development a…
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