The ProstateHumansMalePhenylthiohydantoinAndrogen AntagonistsNitriles
The Germline HSD3B1 Variant Is Associated With Response to Androgen Deprivation Therapy and Abiraterone but not With Response to Enzalutamide in Chinese Prostate Cancer Patients.
Ruofan Shi, Qijun Du, Chi Yao, Da Huang, Xiaohao Ruan, Adrian Chun Yin Lam, Kuen Chan, Tsun Tsun Stacia Chun, Yuguang Philip Wu, Tsz Yeung Kam, Salida Ali, Danfeng Xu, Rong Na
Published: 202610.1002/pros.70089
Abstract
BACKGROUND: To investigate the role of HSD3B1 germline variant (1245C) in hormone therapy outcomes in Chinese prostate cancer (PCa) patients. METHODS: A multi-center observational study was conducted enrolling 785 PCa patients who received primary an…
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