Pharmacoepidemiology and drug safetyHumansFemalePregnancyAntifungal AgentsPregnancy Trimester
Risk of Major Congenital Malformations Associated With First-Trimester Exposure to Topical Antifungal Medications: A Large Claims Database Study.
Tadaharu Kunitoki, Takamasa Sakai, Tomofumi Ishikawa, Ryo Obara, Kei Morishita, Azusa Hara, Motohiko Adomi, Haruto Watanabe, Kaya Hayasaka, Yuna Yoshida, Aki Shimizu, Genki Shinoda, Aoi Noda, Mami Ishikuro, Masatsugu Orui
Published: 202510.1002/pds.70274
Abstract
PURPOSE: Vulvovaginal candidiasis is highly prevalent among pregnant women, and its treatment is crucial. However, there is a lack of evidence regarding the risks on fetal outcomes associated with the use of antifungal medications during the first tr…
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