The Journal of pathology
Truncated FOS impairs osteogenic differentiation and induces prostaglandin and NFκB signalling in an in vitro cell-of-origin model for osteoid osteoma and osteoblastoma.
Suk Wai Lam, Tatiana Belova, Natasja Franceschini, Brendy van den Akker, David Gp van IJzendoorn, Harald Mm Mikkers, Hailiang Mei, Anne-Marie Cleton-Jansen, Marieke L Kuijjer, Karoly Szuhai, Judith Vmg Bovée
Published: 202510.1002/path.70010
Abstract
Osteoid osteoma and osteoblastoma are non-malignant bone-forming tumours of the skeleton, characterised by the presence of irregular trabeculae of woven bone. Rearrangements in FOS, and less frequently FOSB, have recently been identified in osteoid o…
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