Obesity (Silver Spring, Md.)HumansMaleFemaleTwinsMonozygotic
Sex-Specific Subcutaneous Adipose Tissue Transcriptome in Obesity: Insights From Monozygotic Twin Pairs Discordant for BMI.
Hanna Haltia, Maheswary Muniandy, Sini Heinonen, Sina Saari, Marcus Alvarez, Antti Hakkarainen, Jesper Lundbom, Juho Kuula, Per-Henrik Groop, Jaakko Kaprio, Päivi Pajukanta, Kirsi H Pietiläinen, Birgitta W van der Kolk
Published: 202610.1002/oby.70078
Abstract
OBJECTIVE: We investigated the impact of sex on the subcutaneous adipose tissue (AT) transcriptome and its obesity-related adaptations. METHODS: We studied rare BMI-discordant monozygotic twin pairs (ΔBMI > 2.5 kg/m2; 21 female, 16 male pairs) to ass…
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