Movement disorders clinical practice
Evaluating the Role of α-Synuclein Seed Amplification as a Disease Progression Marker: Evidence and Uncertainties.
Daniel Belete, Christian Mattjie, Brook Huxford, Jonathan P Bestwick, Alastair J Noyce, Cristina Simonet
Published: 202510.1002/mdc3.70434
Abstract
BACKGROUND: α-synuclein seeding amplification assay (α-synuclein SAA) development as a diagnostic biomarker for Parkinson's disease (PD) has shown promising results over the past decade. However, the utility of these assays in the prediction of disea…
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