Macromolecular bioscienceNiclosamideHumansHydrogen-Ion ConcentrationPolyestersMethacrylates
Niclosamide Encapsulated pH-Responsive Polyzwitterionic Block Copolymers for Cancer Therapy.
Monu Pandey, Debojit Chakraborty, Shubhra Goel, Josemon Jacob, Jayanta Bhattacharyya
Published: 202610.1002/mabi.202500459
Abstract
Niclosamide (NIC) shows antitumor activity by inhibiting multiple signaling pathways, including signal transducer and activator of transcription 3, Wnt/β-catenin, and NF-κB. However, the poor aqueous solubility and bioavailability limit its potential…
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