Journal of pediatric gastroenterology and nutrition
Methotrexate toxicity and intolerance in paediatric inflammatory bowel disease: A retrospective cohort study.
Eva Vermeer, Eveline L Soetens, Eduard A Struys, Johan E van Limbergen, Maja Bulatović-Ćalasan, Robert de Jonge, Nanne K H de Boer, Tim G J de Meij
Published: 202510.1002/jpn3.70300
Abstract
OBJECTIVES: Methotrexate (MTX) is frequently prescribed in paediatric inflammatory bowel disease (IBD), with routine laboratory monitoring to detect adverse events (AEs), such as hepatotoxicity and myelotoxicity. However, data on the incidence and pr…
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