Journal of periodontology
Peri-implant hypoxia as a potential barrier against ferroptotic mechanisms during peri-implant diseases: A cross-sectional study.
Büşra Yılmaz, Ali Gürkan, Beral Afacan, Harika Atmaca, Timur Köse, Gülnur Emingil
Published: 202510.1002/jper.70001
Abstract
BACKGROUND: Hypoxia modulates inflammation and oxidative stress through hypoxia-inducible factor-1α (HIF-1α). Ferroptosis, an iron-dependent cell death process, is regulated by glutathione peroxidase-4 (GPX4) and involves lipid peroxidation markers l…
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