Journal of medical virologyAntiviral AgentsDrug RepositioningPhlebovirusHumansSimeprevir
Drug Repurposing: In Vitro Evaluation of Simeprevir as a Novel Antiviral Drug Against Severe Fever With Thrombocytopenia Syndrome Virus.
Qian Chen, Jiaxuan Li, Xingxing Wang, Chen Huang, Hao Yan, Jianhua Li, Yanjun Zhang, Keda Chen
Published: 202510.1002/jmv.70655
Abstract
Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV), a tick-borne virus with high mortality, currently lacks approved antiviral therapies. In this study, we evaluated the in vitro activity of 19 FDA-approved drugs against a clinical isolate of…
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