Journal of medical virologyHumansMaleFemaleCOVID-19Systemic Inflammatory Response Syndrome
The Association of RNase L, Cytokines, and Chemokines With Severity of Multisystem Inflammatory Syndrome in Children.
Ting-Yu Yen, Chia-Lang Hsu, Chun-Yi Lu, Ni-Chung Lee, Ming-Tai Lin, Kuan-Ying Arthur Huang, Boon Fatt Tan, Tu-Hsuan Chang, Chun-Min Kang, Wei-Shiung Yang, Bor-Luen Chiang, Li-Min Huang, Hsin-Hui Yu, Luan-Yin Chang
Published: 202510.1002/jmv.70650
Abstract
The 2',5'-oligoadenylate synthetase (OAS)-ribonuclease L (RNase L) system, induced by type I interferons, defends against RNA viruses. Inborn errors in this pathway may trigger inflammatory cytokines, contributing to SARS-CoV-2-related multisystem in…
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