Journal of molecular recognition : JMRGRB7 Adaptor ProteinHumansSignal TransductionNeoplasmssrc Homology Domains
Uncovering the Structural Logic of Grb7: From Domain Mutagenesis to Therapeutic Implications in Cancer Signaling.
Ashis Kumar Biswas, Rajan Koirala, Sharmistha Roy, Trung Nguyen, Barbara A Lyons
Published: 202610.1002/jmr.70019
Abstract
Grb7 is a member of the Grb7 protein family, which also includes Grb10 and Grb14. These adaptor proteins function mainly as scaffolds in phosphorylation-dependent signaling pathways. The family is known to interact with receptor tyrosine kinases and…
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