Journal of molecular recognition : JMRCholinesterase InhibitorsSchiff BasesMolecular Docking SimulationHydrazonesBenzimidazoles
Synthesis, In Vitro Cholinesterase Inhibition, Molecular Docking, Density Functional Theory Analysis of Benzimidazole Based Hydrazone Schiff Bases.
Naqib Ahmad, Nida Ambreen, Muhammad Ayaz, Zainab, Aftab Alam, Imtiaz Ahmad, Ahmed A Elhenawy, Imen Zghab, Syed Adnan Ali Shah, Manzoor Ahmad
Published: 202510.1002/jmr.70012
Abstract
Acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) are the main therapeutic targets for the treatment of neurodegenerative diseases, predominantly Alzheimer's disease. This work reports the synthesis, acetylcholinesterase (AChE) and butyry…
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