Journal of hepato-biliary-pancreatic sciences
High γ-H2AX Predicts Clinical Benefit From Platinum-Based Chemotherapy (mFOLFIRINOX) at Recurrence After Pancreatic Cancer Resection.
Takashi Matsumoto, Zhao Liu, Kosuke Kanemitsu, Hiromitsu Hayashi, Toru Takematsu, Shinsei Yumoto, Yuki Kitano, Shigeki Nakagawa, Kosuke Mima, Hirohisa Okabe, Masaaki Iwatsuki
Published: 202510.1002/jhbp.70032
Abstract
BACKGROUND: Postoperative regimen selection between mFOLFIRINOX and GnP for recurrent pancreatic ductal adenocarcinoma (PDAC) lacks evidence, highlighting the need for a simple biomarker. This study explores the impact of γ-H2AX overexpression, a DNA…
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