Journal of cellular physiologyHumansProto-Oncogene Proteins c-aktHead and Neck NeoplasmsSignal TransductionCell Movement
TTC7B Activates the AKT-JKAMP Signaling Axis to Promote Tumor Progression in Head and Neck Cancer.
Yu-Hsuan Lin, Chih-Yu Chou, Pei-Lun Yu, Yi-Fang Yang
Published: 202510.1002/jcp.70121
Abstract
The tetratricopeptide repeat domain 7 (TTC7) family, comprising the paralogs TTC7A and TTC7B, encodes scaffold proteins that are critical for membrane signaling and cellular homeostasis. Although mutations in TTC7 family have been implicated in immun…
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