Journal of cellular physiologySpinal Cord InjuriesHumansAnimalsCell CommunicationAstrocytes
From Single-Cell Atlas to Functional Validation: Critical Next Steps for Understanding Tip Cell-Mediated Communication in the Injured Spinal Cord.
DuJiang Yang, Jiexiang Yang, GuoYou Wang
Published: 202510.1002/jcp.70117
Abstract
In their recent study, Zeng et al. (2025) employed single-cell RNA sequencing to delineate the landscape of spinal cord injury (SCI), highlighting a previously underappreciated communicative role for endothelial tip cells in engaging astrocytes and m…
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