Journal of cellular physiologyAnimalsHepatocytesMethyltransferasesMiceKnockout
Mettl14 Deficiency Promotes Fam32a Expression via m6A Modifications to Facilitate the Hepatocyte G1/S Transition.
Chengyu Li, Wenhan Zhou, Dayu Wang, Zhaojun Liu, Ming Shen, Linjie Zhu, Hongmin Li, Xiang Zhong, Honglin Liu
Published: 202510.1002/jcp.70102
Abstract
Mettl14, a key component of the m6A methyltransferase complex, plays a crucial role in regulating mRNA stability and splicing. Reduced expression of Mettl14 is associated with hepatocellular carcinoma and liver regeneration, yet the molecular mechani…
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