Journal of biochemical and molecular toxicologyHumansDiethylhexyl PhthalateMyocardial InfarctionMachine LearningSingle-Cell Analysis
Integrating Single-Cell Sequencing, Machine Learning, and Molecular Docking to Elucidate the Molecular Network Linking Myocardial Infarction and DEHP Exposure.
Qianchen Wang, Jiejie Wu, Shaoyu Qi, Jingwen Zhang, Yang Liu
Published: 202610.1002/jbt.70663
Abstract
Di-(2-ethylhexyl) phthalate (DEHP), a pervasive environmental plasticizer, is detected in humans through dietary intake, inhalation, and dermal contact. Epidemiological evidence links urinary DEHP metabolites (e.g., MEHHP and MEOHP) to cardiovascular…
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