Journal of biochemical and molecular toxicologyPyrimidinesGlutathione TransferaseMolecular Docking SimulationAntioxidantsMolecular Dynamics Simulation
Pyrimidine Based Inhibitors Targeting Glutathione S-Transferase in Phase II Detoxification: Antioxidant, ADMET, Docking, and Molecular Dynamics Evaluation.
Fikret Türkan, Adnan Cetin, Meryem Ayan Ustun
Published: 202510.1002/jbt.70652
Abstract
The present study has been conducted to investigate the inhibitory effects and antioxidant capacities of two pyrimidine derivatives, 4,6-Dichloro-2-(methylthio) pyrimidine-5-carbonyl chloride (p1) and 4,6-Dichloro-2-(methylthio) pyrimidine-5-carboxya…
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