Journal of biochemical and molecular toxicologyHumansMethyltransferasesLung NeoplasmsDrug ResistanceNeoplasm
METTL14 Mediates Malignant Progression and Docetaxel Resistance of Lung Cancer by Regulating DKK4 Expression Through m6A Methylation Modification.
Xueliang Yang, Yongming Song, Quan Sun, Fei Han, Xiaofei Zhuang
Published: 202510.1002/jbt.70587
Abstract
Docetaxel (DTX) is widely used in lung cancer (LC), but its therapeutic efficacy is limited due to frequent development of chemoresistance. Epigenetic regulation via N6-methyladenosine (m6A) has been implicated in tumor progression and drug resistanc…
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