Journal of biochemical and molecular toxicologyAnimalsFemaleMiceHypoxia-Inducible Factor 1alpha Subunit
Combined Exposure to High-Cholesterol Diet and PM2.5: Brain Injury, Behavioral Alteration and Regulatory Mechanism of HIF-1α in Female Mice.
Wenqi Chen, Shanshan Chen, Lirong Bai, Lifang Zhao, Mei Zhang, Chuan Dong, Zhu Yang, Yuanyuan Song, Ken Kin Lam Yung, Zongwei Cai, Ruijin Li
Published: 202510.1002/jbt.70568
Abstract
Both high-cholesterol diet (HCD) and fine particulate matter (PM2.5) exposure are associated with increased stroke risk; however, their combined effects-particularly in females-remain poorly understood. This study aimed to investigate the synergistic…
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