Journal of biochemical and molecular toxicologyCarbonic Anhydrase InhibitorsAcetylcholinesteraseCholinesterase InhibitorsHumansMolecular Docking Simulation
Novel Isoindole-1,3-Dione-Isoxazole Hybrids: Synthesis, Characterization, Evaluation of Their Inhibitory Activities on Carbonic Anhydrase and Acetylcholinesterase.
Özlem Gündoğdu Aytaç, Hilal Başak Gündoğdu, Sertan Aytaç, Zeynebe Bingöl, İlhami Gülçin, Yunus Kara
Published: 202510.1002/jbt.70550
Abstract
It is known that compounds containing isoxazole units exhibit a high potential for biological activity due to the isoxazole ring. In this study, eight hexahydro-5H-isoxazolo[4,5-f]isoindole-5,7(6H)-dione derivatives bearing isoxazole moieties were sy…
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