Journal of biomedical materials research. Part AMesenchymal Stem CellsInduced Pluripotent Stem CellsCell DifferentiationHumansCell Proliferation
Decellularized Extracellular Matrix Produced by iPSC-Derived MSCs Promotes iPSC-MSC Proliferation and Differentiation and Regulates Secreted Factors.
Tao Huang, Michael Yang, Claire Grant, Kilian Kelly, Andrea J O'Connor, Bill Kalionis, Daniel E Heath
Published: 202510.1002/jbma.70010
Abstract
The in vitro expansion of mesenchymal stromal cells (MSCs) is essential to produce clinically relevant quantities of cells while preserving therapeutic potential. Currently, premature senescence of the MSCs during in vitro expansion is a significant…
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