Journal of applied toxicology : JAT
Acute Toxicological Evaluation in Alternative Method Galleria mellonella and Murine Models of the Betulinic Acid Derivatives.
Elenilson F Silva, Jessica Gotardi, Gloria N S Silva, Aline R Zimmer, Alexandre J Macedo, Rodrigo C Silva, Bianca B Prunes, Fernanda Visioli, Simone C B Gnoatto
Published: 202510.1002/jat.70040
Abstract
Betulinic acid (BA) has been described with several therapeutic properties, including anticancer, anti-inflammatory, antibacterial, antiviral, antidiabetic, antimalarial, and anti-HIV activities. Unfortunately, the long-term use of BA can cause mild…
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