Journal of applied toxicology : JAT
The Effect and Its Mechanism of a Novel Disintegrin GbvIV4 From Gloydius brevicaudus Venom on Inhibition Metastasis of Melanoma Cells.
Jiayi Zhou, Qi Deng, Ting Peng, Ningning Zhao, Zhexi Xu, Yunlu Xu
Published: 202510.1002/jat.4990
Abstract
Tumor metastasis, a hallmark of advanced cancer, depends on integrin-mediated adhesion and migration. Disintegrins, RGD-containing peptides from snake venom, are potent integrin antagonists with antimetastatic potential. This study characterizes GbvI…
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