IUBMB lifeHumansTumor Suppressor Protein p53Epithelial-Mesenchymal TransitionBreast NeoplasmsFemale
Capturing the Variations in Mutant p53-Driven Regulatory Networks in Breast Cancer Subtypes, Its Clinical Relevance and a Novel Association With Androgen Receptor and EMT.
Aastha Singh, Rahul Gupta, Ritu Kulshreshtha
Published: 202610.1002/iub.70081
Abstract
The tumour suppressor TP53 is frequently mutated in breast cancer and drives poor outcomes. The impact of mutant p53 (mutp53) on subtype-specific gene and non-coding RNA networks, and their clinical significance, remains largely underexplored. Here,…
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