The Effect of Hypnotherapy on the Resilience of Women With Polycystic Ovarian Syndrome: Study Protocol for a Randomized Controlled Trial.

Background and Aims: Polycystic ovarian syndrome, with a mean incidence of 5-10, is the most common endocrine disorder affecting women of reproductive age. These patients suffer from a wide range of symptoms that are inversely related to their resilience and quality of life. Thus, this study protocol was prepared to determine the effect of hypnotherapy intervention on the resilience of patients with polycystic ovary syndrome. Methods: The current study protocol is a randomized clinical trial. In total, 56 women diagnosed with polycystic ovarian syndrome will be invited to participate in a 6-week intervention. After allocating the samples to two control and intervention groups using a block randomized design, for each subject in the intervention group, 6 weekly sessions of hypnotherapy will be held for 40-60 min, and for the control group, routine care will be provided. In this study, the level of patient resilience will be measured as the primary outcome using the Connor-Davidson Resilience Scale (CD-RIS). Analysis will be conducted using SPSS V.26. To compare variables between intervention and control groups according to the qualitatively and quantitatively variable nature, the χ 2 test (if the default is not established, Fisher's exact test) and t-test of two independent samples, analysis of variance, or its non-parametric equivalent (Mann-Whitney and Kruskal-Wallis) will be used, respectively. Discussion: This plan focuses on the resilience and quality of life in women with polycystic ovarian syndrome. Considering that hypnotherapy is safe and relatively inexpensive, and has almost no side effects, it is very important to determine whether women with polycystic ovary syndrome could benefit from this psychological technique. Trial Registration: Iranian Clinical Trial Register IRCT20161126031117N12; Registered V1.0 on May 4, 2022.