The Landscape of Radiofrequency Technology for Skin Rejuvenation.

Background and Aims: Aging skin is characterized by reduced tissue volume, weakened fibrous support, and increased laxity, leading to wrinkles and sagging. While surgical methods are effective, noninvasive techniques like radiofrequency (RF) have gained popularity due to their safety, minimal recovery time, and natural-looking results. This review aims to elucidate the mechanisms, classifications, and clinical efficacy of monopolar, bipolar, and multipolar RF systems in skin rejuvenation. Methods: A systematic review was conducted in electronic databases, including PubMed and Web of Science, to comprehensively analyze the literature on radiofrequency for skin rejuvenation. The methodologies, outcomes, and conclusions of the identified studies were summarized and compared. Results: RF technology delivers targeted thermal energy to the dermal layer, inducing collagen contraction and stimulating neocollagenesis, thus improving skin texture and elasticity. Monopolar RF achieves deep tissue penetration (up to 20 mm) but requires precise energy modulation to minimize discomfort. Bipolar RF offers localized treatment with reduced penetration depth (1-4 mm), enabling safer home-use applications. Multipolar RF, particularly microneedle-based systems, combines mechanical injury with thermal remodeling to enhance collagen production while sparing epidermal integrity. Despite the high safety profile, potential risks and complications exist, emphasizing the need for individualized treatment and experienced practitioners. Conclusion: Radiofrequency technology is an integral component of skin rejuvenation, whose efficacy depends critically on the customization of treatment parameters and the expertise of the practitioner. Future research should focus on optimizing parameters, elucidating underlying mechanisms, and exploring combination therapies to further enhance clinical efficacy.