European journal of pain (London, England)AnimalsCannabidiolDrosophila melanogasterNociceptionDisease Models
The parabss1 Drosophila melanogaster as Model for Chronic Nociception: Insights Into Cannabidiol Analgesic Effects.
Serena Mares Malta, Lucas Ian Veloso Correia, Alexandre Souza Marquez, Lucas Matos Martins Bernardes, John George Howland, Ana Paula Mendes-Silva, Foued Salmen Espíndola, Carlos Ueira-Vieira
Published: 202610.1002/ejp.70225
Abstract
BACKGROUND: Chronic pain, which is often unrelated to ongoing injury, is poorly understood and difficult to treat. Genetic studies have identified voltage-gated sodium (Nav) channels, particularly gain-of-function mutations such as L858F and R1150W i…
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