European journal of immunologyHumansT-LymphocytesRegulatoryAnimalsPurines
Purin Metabolism Is Crucial for Regulatory T Cell Stability and Function.
Young S Lee, Marina W Shirkey, Vikas Saxena, Dejun Kong, Bing Ma, Reza Abdi, Jonathan S Bromberg
Published: 202510.1002/eji.70070
Abstract
Cellular metabolism intricately directs the differentiation, stability, and function of regulatory T cells (Tregs), which are pivotal in immune regulation. Metabolic reprogramming enables Tregs to adapt to diverse tissue environments; however, it can…
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