Clinical pharmacology and therapeuticsHumansAldosteroneCytochrome P-450 CYP11B2ModelsBiological
Insights Into Aldosterone Regulation Through Pharmacokinetic-Pharmacodynamic Modeling of an Aldosterone Synthase Inhibitor.
Javiera Cortés-Ríos, William J Jusko
Published: 202610.1002/cpt.70114
Abstract
Aldosterone is a mineralocorticoid hormone essential for regulating renal function and blood pressure. Despite its clinical relevance, key aspects of aldosterone pharmacokinetics (PK) and physiological dynamics remain incompletely understood. In seri…
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