Chemphyschem : a European journal of chemical physics and physical chemistryProtein Kinase InhibitorsProtein Serine-Threonine KinasesMolecular Dynamics SimulationHumansLigands
Exploring the Structural Dynamics of SRPK1 to Identify Competitive Inhibitors via Molecular Modeling Techniques.
Shreya Mukherjee, Abhishek Bera, Niladri Patra
Published: 202610.1002/cphc.202500204
Abstract
Upregulation of serine arginine protein kinase 1 (SRPK1), a protein responsible for phosphorylation of Ser-Arg rich residues aimed at SR proteins, is associated with apoptosis, poor survival, etc. Catalytic sites of the kinase proteins are incompeten…
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