Clinical pharmacology in drug developmentHumansMaleAdultFemaleCytochrome P-450 CYP3A Inhibitors
Effects of Gastric Acid Suppression, Cytochrome P4503A Inhibition and Induction, and Food on the Pharmacokinetics of Tinlarebant in Healthy Adults.
Thomas M Polasek, Kushal J Paneliya, Tom Lin, Nathan L Mata, Irene Wang, Hendrik P Scholl, Jessyca Lin
Published: 202610.1002/cpdd.70009
Abstract
Tinlarebant is an oral retinol binding protein 4 antagonist in clinical development for geographic atrophy, an advanced stage of dry age-related macular degeneration, and Stargardt disease, an inherited juvenile-onset macular degeneration. A randomiz…
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