CancerHumansKiller CellsNaturalMaleFemale
Natural killer cell infiltration elicits gender-dependent dichotomous clinical outcomes in urothelial carcinoma.
Lingkai Zhang, Zhaopei Liu, Yawei Ding, Jiaxing Sun, Yuzhen Wu, Xiaohe Su, Kaifeng Jin, Han Zeng, Hailong Liu, Yuan Chang, Yu Zhu, Zewei Wang, Le Xu, Weijuan Zhang, Jiejie Xu
Published: 202510.1002/cncr.70196
Abstract
BACKGROUND: Sex differences are a hallmark of urothelial carcinoma (UC), and profoundly influence disease progression and therapeutic outcomes. As critical effector immune cells with intrinsic sexual dimorphism, the contributions of natural killer (N…
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