ChemMedChemHumansAlzheimer DiseaseBenzoxazolesDrug DesignCholinesterase Inhibitors
Benzoxazole Derivatives as Dual p38α Mitogen-Activated Protein Kinase and Acetylcholinesterase Inhibitors: Design, Synthesis, and Evaluation for Alzheimer's Disease and Cancer Therapy.
Bayan Zoatier, Gizem Yildiztekin, Mehmet Abdullah Alagoz, Ceylan Hepokur, Esra Dilek, Oztekin Algul
Published: 202510.1002/cmdc.202500669
Abstract
Alzheimer's disease (AD), the most prevalent form of dementia, leads to progressive cognitive decline due to pathological hallmarks including amyloid plaques, neurofibrillary tangles, synaptic loss, neuroinflammation, and neuronal cell death, highlig…
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