ChemMedChemProdrugsAnimalsAntineoplastic AgentsMiceFerroptosis
Delivery of a GPX4 Inhibitor by SN38 Prodrug Nanoassemblies for Amplified Antitumor Efficacy Based on Ferroptotic Chemotherapy.
Lin Li, Yanyan Wu, Weiwei Wang, Kejing Wang, Lin Chen
Published: 202510.1002/cmdc.202500667
Abstract
Prodrug-based self-assembled nanoassemblies, with carrier-free structures and high drug loading, are garnering attention for chemotherapy. Additionally, the synergistic effects of prodrug nanoassemblies combined with multiple cell death pathways dese…
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