Boron-Enolate Enabled Chemoselective Twofold Allylation of Alkenyl-Keto-Imines Using Allylboronic Acids: Asymmetric Construction of Nonadjacent Stereocenters.

A twofold allylation strategy is developed for the efficient synthesis of chiral α-amino-ketones bearing both adjacent and nonadjacent stereocenters including quaternary ones. Both linear and branched-allyl moieties were incorporated using either sam…

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