Zinc Phosphide Poisoning in Pregnancy: A Rare Case Report From Nepal.
Nabin Pahari, Sushant Shrestha, Sagun Ghimire, Mukesh Pahari, Anmol Singh Shrestha, Sahas Chhetri, Mrinal Silwal
Abstract
Open AccessZinc phosphide (Zn3P2) poisoning during pregnancy is exceedingly unusual and potentially lethal, with no previously known occurrences globally. We present a 26-year-old woman, gravida 2 para 1, at 29 weeks gestation, who took 15 g of Zn3P2 in a suicidal attempt and experienced non-projectile vomiting. Her vital signs were stable (BP 110/80 mmHg, GCS 15/15), but she experienced transitory hepatic dysfunction that improved on Day 4 with supportive therapy such as coconut oil gastric lavage, intravenous fluids, and pantoprazole. The fetal scan confirmed viability (heart rate of 158 bpm). The high mortality of Zn3P2 (37%-100%) is caused by phosphine gas-induced suppression of mitochondrial respiration. This case emphasizes the lack of a particular antidote and the significance of immediate decontamination, hepatic monitoring, and mental follow-up following purposeful consumption.