Clinical case reports
Neuroleptic Malignant Syndrome: A Case Report of the Oldest Man in Literature.
Forouzan Elyasi, Mohsen Aarabi, Majidreza Adelani, Arghavan Fariborzifar, Marzieh Azizi
Published: 202510.1002/ccr3.71206
Abstract
Open AccessA diagnosis of neuroleptic malignant syndrome (NMS) was made in a 96-year-old man, representing the oldest documented case in the existing medical literature. Even at very low doses of antipsychotic medications, older adults are more likely to develop NMS. This increased susceptibility may exacerbate other risk factors, such as preexisting neurological disorders or the concurrent use of cholinesterase inhibitors.